Domain Definition Protein
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One domain may appear in a variety of different proteins.
Domain definition protein. Molecular evolution uses domains as building blocks and these may. What are protein domains. Usually they are responsible for a particular function or interaction contributing to the overall role of a protein.
Many proteins consist of several domains. A domain may be characterized by the following. Each domain forms a compact folded three dimensional structure.
Rather than relying on pairwise sequence alignments domain annotation uses models that represent conserved protein regions. 3 often has a specific function associated with it. Protein domain annotation is an alternative approach to sequence similarity searches.
These conserved regions are inferred from multiple sequence alignments of database proteins and have higher theoretical sensitivity. Domains are distinct functional and or structural units in a protein.
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